PA-PRP : Platelet Rich Plasma are photo activation before injection back into the patient. For photo activation low intensity light at specific frequencies are uses.
Photo activation of PRP increase the secretion of various inflammatory and healing agents from peripheral blood cells and platelet into PRP Photo activation seems to increase the secretion of tiny vesicles (exosomes) from peripheral white blood cells, stem cells and platelets. Photo activation raises IL-1 Receptor antagonist in PRP.
PDGF (Platelet Derived Growth Factor)Cell growth, differentiation, blood vessel growth
|TGF-β (Transforming Growth Factor-beta)||Blood vessel, collagen synthesis|
|VEGF (Vascular Endothelial Growth Factor)||Cell growth, migration, new blood vessel growth|
|FGF (Fibroblast Growth Factor)||Collagen synthesis, blood vessel growth|
|EGF (Endothelial Growth Factor)||New blood vessel growth, cell growth|
|IGF (Insulinlike Growth Factor)||Collagen synthesis with PDGF, cell growth, differentiation|
PRP also contain:
- Anti-inflammatory and anti microbial mediators
- IL-1 Receptor antagonist
- Thymosin beta 4-TNF blocker
- Microbiocidal Peptides
- Phospholipade A2
- Thromboxane A2